GB/T 44480-2024 化学品 丽斑麻蜥急性经口毒性试验

ICS

13.300

CCS

A80

中华人民共和国国家标准

GB/T44480—2024

化学品丽斑麻蜥急性经口毒性试验

Chemicals—Eremiasargusacuteoraltoxicitytest

2024-09-29发布2025-04-01实施

国家市场监督管理总局发布

国家标准化管理委员会

GB/T44480—2024

目次

前言

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范围

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规范性引用文件

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术语和定义

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试验概述

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试验方法

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5.1

材料和仪器

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5.2

样品制备

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5.3

试验操作

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结果计算与表示

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质量保证和质量控制

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试验报告

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附录A（资料性）丽斑麻蜥的驯养繁殖条件及方法录A方法

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附录B（资料性）溶液配制及试验观察记录表

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参考文献

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GB/T44480—2024

前言

本文件按照GB/T1.1—2020《标准化工作导则第1部分：标准化文件的结构和起草规则》的规

定起草。

请注意本文件的某些内容可能涉及专利。本文件的发布机构不承担识别专利的责任。

本文件由全国危险化学品管理标准化技术委员会（SAC/TC251）提出并归口。

本文件起草单位：中国科学院生态环境研究中心、中检科健（天津）检验检测有限责任公司、中国

检验检疫科学研究院。

本文件主要起草人：常静、王会利、万斌、谢昀、李建中、周丽丽、刘春艳、王利利。

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GB/T44480—2024

化学品丽斑麻蜥急性经口毒性试验

1范围

本文件描述了化学品对丽斑麻蜥急性经口毒性试验的试验方法，规定了试验的材料、条件、操作、

质量控制、数据处理、试验报告等的基本要求。

本文件适用于测试化学品对丽斑麻蜥的急性毒性效应。

2规范性引用文件

下列文件中的内容通过文中的规范性引用而构成本文件必不可少的条款。其中，注日期的引用文

件，仅该日期对应的版本适用于本文件；不注日期的引用文件，其最新版本（包括所有的修改单）适用

于本文件。

GB/T6682分析实验室用水规格和试验方法

GB/T31270.9—2014化学农药环境安全评价试验准则第9部分：鸟类急性毒性试验

3术语和定义

下列术语和定义适用于本文件。

3.1

半数致死剂量medianlethaldose；LD50

一次给予实验用动物供试物后，引起实验用动物总体中半数死亡的毒物统计学剂量。以实验用动物

单位体重接受供试物的质量表示。

3.2

最高无致死剂量maximumnonlethaldose；LD0

一次给予实验用动物供试物后，不引起实验用动物死亡的最高毒物统计学剂量。以实验用动物单位

体重接受供试物的质量表示。

3.3

最低全致死剂量minimumtotallethaldose；LD100

一次给予实验用动物供试物后，引起实验用动物全部死亡的最低毒物统计学剂量。以实验用动物单

位体重接受供试物的质量表示。

3.4

急性经口毒性acuteoraltoxicity

一次经口给予实验用动物供试物后，动物在短期内（7d）出现的健康损害效应。

3.5

供试物testsubstances

由各种元素组成的纯净物或混合物。

4试验概述

将一系列不同浓度的供试物以一次经口的方法灌注给丽斑麻蜥，以7d为试验周期，每天记录试验

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